Extracellular mutation induces an allosteric effect across the membrane and hampers the activity of MRP1 (ABCC1)

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Bin Kanner, Y., Ganoth, A., Tsfadia, Y.

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https://www.nature.com/articles/s41598-021-91461-3#citeas

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From virus to diabetes therapy: Characterization of a specific insulin-degrading enzyme inhibitor for diabetes treatment​

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Nash, Y., Ganoth, A., Borenstein-Auerbach, N., Levy-Barazany, H., Goldsmith, G., Kopelevich, A., Pozyuchenko, K., Sakhneny, L., Lazdon, E., Blanga-Kanfi, S., Alhadeff, R., Benromano, T., Landsman, L., Tsfadia, Y., Frenkel, D.

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https://faseb.onlinelibrary.wiley.com/doi/abs/10.1096/fj.201901945R

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A dual and conflicting role for imiquimod in inflammation: A TLR7 agonist and a cAMP phosphodiesterase inhibitor

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Ernst, O., Failayev, H., Athamna, M., He, H., Tsfadia, Y., Zor, T.

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https://www.sciencedirect.com/science/article/pii/S0006295220304421

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Structure-guided probing of the leukotriene C4 binding site in human multidrug resistance protein 1 (MRP1; ABCC1)

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Conseil, G., Arama, M., Tsfadia, Y., Cole, S. P. C

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https://faseb.onlinelibrary.wiley.com/doi/full/10.1096/fj.201900140R

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An Outward-Facing Aromatic Amino Acid Is Crucial for Signaling between the Membrane-Spanning and Nucleotide-Binding Domains of Multidrug Resistance Protein 1 (MRP1; ABCC1)

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Weigl, K. E., Conseil, G., Rothnie, A. J., Arama, M., Tsfadia Y. and Cole S. P. C

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​https://molpharm.aspetjournals.org/content/94/3/1069

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The involvement of Coordinative Interactions in the Binding of Dihydrolipoamide Dehydrogenase to Titanium Dioxide – localization of a Putative Binding Site

 

Dayan, A., Babin, G., Ganoth, A., Kayouf, N. S., Nitoker-Eliaz, N., Mukkala, S., Tsfadia, Y. and Fleminger, G.          

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Journal of Molecular Recognition 10.1002/jmr.2617 (2017)

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The Translocation of Na+ Ion inside Human Thrombin Accounts for the Activation of the Enzyme

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Gdalia, H., Nachliel, E., Gutman, M., Einav, Y. and Tsfadia, Y.

 

Israel Journal of Chemistry 10.1002/ijch.201600128 (2017)

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The Effect of Regulating Molecules on the Structure of the PPAR-RXR Complex

 

Amber-Vitos, O., Chaturverdi, N., Nachliel, E., Gutman, M., and Tsfadia, Y.

 

Biochimica et Biophysica Acta 10.1016/j.bbalip (2016)

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The Interaction of FABP with Kapα

 

Amber-Vitos, O., Kucherenko, N., Nachliel, E., Gutman, M., and Tsfadia, Y.

 

Plos One 10.1371/journal.pone.0132138 (2015)

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Structural Characterization of the Drug Translocation Path of MRP1/ABCC1

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Amram, S., Ganoth, A., Tichon, O., Peer, D., Nachliel, E., Gutman, M., and Tsfadia, Y.

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Israel Journal of Chemistry 10.1002/ijch.20130032 (2014)

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A Single Disulfide Bond Disruption in the β3 Integrin Subunit Promotes  Thiol/Disulfide Exchange, a Molecular Dynamics Study

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Levin, L., Zelzion, E., Nachliel­­,  E., Gutman, M., Tsfadia, Y.,­ and Einav, Y.

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Plos One 10.1002/ijch.201300132 (2013)

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Ubiquitin: Molecular Modeling and Simulations

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Ganoth, A., Tsfadia, Y., and Wiener, R.

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Journal of Molecular Graphics and Modelling 10.1016/j.jmgm.2013.09.006 (2013)

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Tracking the Interplay Between Bound Peptide and the lid Domain of DnaK, Using Molecular Dynamics

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Azoulay, I., Kucherenko, N., Nachliel, E., Gutman, M., Azem, A., and Tsfadia, Y.

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International Journal of Molecular Sciences 10.3390/ijms140612675 (2013)

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Insight into the Interaction Sites Between Fatty Acid Binding Proteins and their Ligands

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Levin, LB, Ganoth A, Amram S, Nachliel E, Gutman M, and Tsfadia Y.

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Journal of Molecular Modeling 10.1007/s00894-009-0599-6 (2010)

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Interaction of the Tim44 C-terminal Domain with Negatively Charged Phospholipids

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Marom, M., Safonov, R., Amram, S., Avneon, Y., Nachliel, E., Gutman, M., Zohary, K., Azem, A., and Tsfadia, Y.

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Biochemistry 10.1021/bi900998v (2009)

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Molecular Dynamics Study of the Interaction Between Fatty Acid Binding Proteins with Palmitate Mini-micelles

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Levin, L. B., Nachliel, E., Gutman, M., and Tsfadia, Y.

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Molecular and Cellular Biochemistry 10.1007/s11010-008-0010-4 (2009)

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Cross-linking with Bifunctional Reagents and its Application to the Study of the Molecular Symmetry and the Arrangement of Subunits in Hexameric Protein Oligomers

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Azem, A., Tsfadia, Y., Hajouj, O., Shaked, I. and Daniel, E.

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Biochimica et Biophysica Acta 10.1016/j.bbapap.2009.11.024 (2009)

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Molecular Dynamics Simulations of Palmitate Entry into the Hydrophobic Pocket of the Fatty Acid Binding Protein

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Tsfadia, Y., Friedman, R., Kadmon, J., Selzer, A., Nachliel, E., Gutman, M.

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FEBS Letters 10.1016/j.febslet.2007.02.033 (2007)

 

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